Quotes:

"If I like myself at this weight, then this is what I’m going to be. I don’t have an eating disorder."
"It's important to be able to depend upon people, to never doubt their intentions. Friends need to know they can be themselves without being judged."
"If there's a hair on my food, I'm one of those people who will eat the food anyway."
"I can't just be with someone just because it's great sex. Because orgasms don't last long enough."
"A lot of my humor does come from anger. It's like, you're not gonna pull one over on me - which is pretty much my motto anyways."
"I'm a firm believer that if you feel good, there's nothing you can't do."
"I don't think I'm too thin at all. I understand when people say, 'Well your face gets gaunt,' but to get your bottom half to be the right size, your face might have to be a little gaunt. You choose your battles."
"I don't want to feel I'm responsible for anorexia across the country."
"I like to walk into a house and go, 'Rip up the brown shag carpet and open up that wall with some French doors.'"
"I only have to do three things to look halfway decent, curl my eyelashes, fill in my eyebrows and put some lipstick on."
"I think I look very healthy. You've already seen what I've eaten, so I couldn't be anorexic, and I wouldn't throw up if you paid me $1,000, so I'm not bulimic. Okay, for $1,000 I would stick my finger down my throat, but throwing up is the worst thing in the world."
"I would like to do a part that would stretch me. In America it seems to me that you just take your clothes off and that helps, but I wouldn't want to do that."
"I'm a gemini, and I get so bored so easily. I mean, I have moved six times in the last eight years."
"I'm a very open person. I know I open my mouth way too much, but I just do that."
"I'm not a huge fan of romantic comedimes- my taste goes much more to the offbeat and dark. I'd love to sink my teeth into something like 'Fargo'"
"I'm not going to deny it. I'm a neat person, there's no question. But I don't become obsessed with it."
"If I like myself at this weight, then this is what I'm going to be. I don't have an eating disorder."
"When David Arquette and I got engaged we started therapy together. I'd heard that the first year of marriage is the hardest, so we decided to work through all that stuff early."
"Friends changed my life in so many ways. It gave me opportunity. It gave me freedom. It gave me a family of close Friends with whom I've grown up. It taught me about comedy. It taught me about relationships. It taught me about everything." - People April 19, 2004.
"If you wear lipstick and pluck your eyebrows, you could wear nothing else." - US, September 1994.
"My father, when you were with him, gave you so much attention. It might only last for a minute, but for that minute you felt like you were the greatest thing that ever hit the earth. But then he was gone. I used to go, 'Dad, watch me jump off the diving board. I can do a flip. Watch!' and I'd start to do it, and by the time you were at the end of the diving board, he'd be looking the other way. And I'd be like, 'Dad, I'm gonna do it again,' 'cause I didn't want the time with my father to be over. I wanted to keep going." - US, July 1996.
"Whoever said aging wasn't for sissies was right," she said. "People who read a magazine can look at the picture and go, 'She looks great for over 40!' But guess what? That's not what I look like. Lighting is everything. When you're in your car and you look in the mirror and the sun's beaming in, you're like, 'Wow, times are getting tough.'" - Life magazine, August 2006
"I like keeping Gale bitchy. She has a reputation to live up to. She may have changed her hair but not much else." about her character Gale Weathers in the Scream series
"I get so bored! I had a treadmill... I gave it to my mom. I had a stairmaster... gone. I had a recumbent bike...I dont know where that is. So I hate exercise except for Pilates."
"A lot of my humor does come from anger. It's like, you're not gonna pull one over on me-which is pretty much my motto anyways."
"I'm not a huge fan of romantic comedimes- my taste goes much more to the offbeat and dark. I'd love to sink my teeth into something like 'Fargo'"
"I only have to do three things to look halfway decent, curl my eyelashes, fill in my eyebrows and put some lipstick on." (similar to one we have)
"I have to be physically attracted to someone. But I can't just be with someone just because it's great sex. Because orgasms don't last long enough."
"Honesty is the key to a relationship. If you can fake that, you're in."
"Before he moved in, David would say 'How are we ever going to meld together, because our tastes are so different? Maybe it's because we're truly in love that we can". - on husband David Arquette
"I want people to be happy, so I think that's one of the reasons why I wanted to do the show in the first place...just to see somebody, even if it's just for the day. To see their life change for that moment when they walk into the room and are that happy. It really makes you cry. It does. I hope I don't lose this feeling." - on producing her show "Mix it Up".

On Monica: "Monica's a really clean person, and I'm not saying I'm not clean because that's kinda gross, to say I'm not clean, because I am. But she's obsessed with being clean and like, so she takes me, and then you times me by 1,000, and that's what she would be like."
She once said "I am Monica"

About playing Monica and Chandler: "It's so much fun for us. I have a new love for the show since I've gotten into this relationship. Honestly, I was a little bored the first four years. I had some fun things to do and some good relationships, but Monica was developing and I felt like there was a lot of straight man stuff. Now we have something really fun to play -two really neurotic people trying to have a relationship. They're both afraid to commit, to get married, or take these steps. I have a really good time playing with him [Matthew Perry]. It's kind of like our relationship in real life - except we don't kiss."